Blar i forfatter "Brodin, Ellen Elisabeth"

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    • Chronic obstructive pulmonary Disease and risk of mortality in patients with venous thromboembolism - the Tromsø Study 

      Børvik, Trond; Brækkan, Sigrid Kufaas; Evensen, Line; Brodin, Ellen Elisabeth; Morelli, Vania Maris; Melbye, Hasse; Hansen, John-Bjarne (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-12-30)
      <i>Background</i> - Previous studies have shown increased mortality in venous thromboembolism (VTE) patients with chronic obstructive pulmonary disease (COPD), but it is unknown to what extent the association is influenced by the severity of COPD and physical inactivity.<p> <p><i>Objectives</i> - This article investigates whether COPD, and stages of COPD, influenced the risk of mortality after a ...

    • Cystatin C is associated with risk of venous thromboembolism in subjects with normal kidney function - the Tromso study 

      Brodin, Ellen Elisabeth; Brækkan, Sigrid Kufaas; Vik, Anders; Brox, Jan; Hansen, John-Bjarne (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
      Background Previous studies have shown an association between impaired kidney function, assessed by cystatin C-based estimated glomerular filtration rate, and venous thromboembolism. The aim of this study was to investigate whether serum cystatin C was associated with a risk of venous thromboembolism among subjects with normal kidney function in a prospective population-based study. Design and ...

    • D-Dimer Measured at Diagnosis of Venous Thromboembolism is Associated with Risk of Major Bleeding 

      Johnsen, Håkon Sandbukt; Hindberg, Kristian; Bjøri, Esben; Brodin, Ellen Elisabeth; Brækkan, Sigrid Kufaas; Morelli, Vania Maris; Hansen, John-Bjarne (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-03-25)
      Identification of patients at risk of major bleeding is pivotal for optimal management of anticoagulant therapy in venous thromboembolism (VTE). Studies have suggested that D-dimer may predict major bleeding during anticoagulation; however, this is scarcely investigated in VTE patients. We aimed to investigate the role of D-dimer, measured at VTE diagnosis, as a predictive biomarker of major bleeding. ...

    • Diagnostic Blood Biomarkers for Acute Pulmonary Embolism: A Systematic Review 

      Wikan, Vårin Eiriksdatter; Tøndel, Birgitte Gladsø; Morelli, Vania Maris; Brodin, Ellen Elisabeth; Brækkan, Sigrid Kufaas; Hansen, John Bjarne (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-07-06)
      (1) Background: The current diagnostic algorithm for acute pulmonary embolism (PE) is associated with the overuse of CT pulmonary angiography (CTPA). An additional highly specific blood test could potentially lower the proportion of patients with suspected PE that require CTPA. The aim was to summarize the literature on the diagnostic performance of biomarkers of patients admitted to an emergency ...

    • Hyperglycemia, Assessed by HbA1c, and Future Risk of Venous Thromboembolism - The Tromsø Study 

      Lerstad, Gunhild; Brodin, Ellen Elisabeth; Enga, Kristin; Jorde, Rolf; Schirmer, Henrik; Njølstad, Inger; Svartberg, Johan; Brækkan, Sigrid Kufaas; Hansen, John-Bjarne (Journal article; Tidsskriftartikkel; Peer reviewed, 2014-03-05)
      Background: Glycated hemoglobin (HbA1c), a marker of average plasma glucose during the last 8-12 weeks, is associated with future risk of cardiovascular disease (CVD) and all-cause mortality. Objectives: To examine the association between hyperglycemia, assessed by HbA1c, and future risk of VTE in a population based cohort. Methods: HbA1c was measured in 16 156 unique subjects (25-87 years) ...

    • Myocardial infarction and future risk of cancer in the general population—the Tromsø Study 

      Rinde, Ludvig Balteskard; Småbrekke, Birgit; Mathisen Hald, Erin; Brodin, Ellen Elisabeth; Njølstad, Inger; Mathiesen, Ellisiv B.; Løchen, Maja-Lisa; Wilsgaard, Tom; Brækkan, Sigrid Kufaas; Vik, Anders; Hansen, John-Bjarne (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-02-07)
      The association between myocardial infarction (MI) and future risk of incident cancer is scarcely investigated. Therefore, we aimed to study the risk of cancer after a first time MI in a large cohort recruited from a general population. Participants in a large population-based study without a previous history of MI or cancer (n = 28,763) were included and followed from baseline to date of cancer, ...

    • A retrospective comparison of ultrasound-assisted catheter-directed thrombolysis and catheter-directed thrombolysis alone for treatment of proximal deep vein thrombosis 

      Tichelaar, Ynse Ieuwe Gerardus Vladimir; Brodin, Ellen Elisabeth; Vik, Anders; Isaksen, Trond; Skjeldestad, Finn Egil; Kumar, Satish; Trasti, Nora; Singh, Kulbir; Hansen, John-Bjarne (Journal article; Tidsskriftartikkel; Peer reviewed, 2016)
      Background: Recent studies have suggested that catheterdirected thrombolysis (CDT) reduces development of postthrombotic syndrome (PTS). Ultrasound-assisted CDT (USCDT) might enhance the efficiency of thrombolysis. We aimed to compare USCDT with CDT on efficacy, safety, development of PTS, and quality of life after longterm follow-up. <p>Methods: We describe a retrospective case series of 94 ...

    • Serum osteoprotegerin and future risk of cancer and cancer-related mortality in the general population: the Tromsø study 

      Vik, Anders; Brodin, Ellen Elisabeth; Mathiesen, Ellisiv B.; Brox, Jan; Jørgensen, Lone; Njølstad, Inger; Brækkan, Sigrid Kufaas; Hansen, John-Bjarne (Journal article; Tidsskriftartikkel; Peer reviewed, 2014)

    • Serum osteoprotegerin and renal function in the general population: The Tromsø Study 

      Vik, Anders; Brodin, Ellen Elisabeth; Mathiesen, Ellisiv B.; Brox, Jan; Jørgensen, Lone; Njølstad, Inger; Brækkan, Sigrid Kufaas; Hansen, John-Bjarne (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-10-03)
      <p><i>Background</i>: Serum osteoprotegerin (OPG) is elevated in patients with chronic kidney disease (CKD) and increases with decreasing renal function. However, there are limited data regarding the association between OPG and renal function in the general population. The aim of the present study was to explore the relation between serum OPG and renal function in subjects recruited from the general ...

    • Thyroid function, as assessed by TSH, and future risk of venous thromboembolism: The Tromsø study 

      Lerstad, Gunhild; Enga, Kristin Fjeldstad; Jorde, Rolf; Brodin, Ellen Elisabeth; Svartberg, Johan; Brækkan, Sigrid Kufaas; Hansen, John-Bjarne (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-04-21)
      Objective: The relationship between thyroid function and the risk of venous thromboembolism (VTE) has not been addressed in population-based cohorts. We investigated the association between TSH levels and the risk of VTE in a general adult population. Design: Population-based cohort study. Methods: TSH was measured in 11 962 subjects aged 25–89 years who participated in Tromsø 4–6 starting in ...